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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T11964 | MCH-1 antagonist 1 | P450 | |
MCH-1 antagonist 1 also inhibits CYP3A4 (IC50: 10μM).MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist (Ki: 2.6 nM). | |||
T11966 | MCHR1 antagonist 2 | HER , Melanin-concentrating Hormone Receptor (MCHR) | |
MCHR1 antagonist 2 is an antagonist of melanin-concentratin hormone receptor 1(MCH1-R, IC50 = 65 nM) and also inhibits hERG. | |||
T22591 | ATC 0175 hydrochloride | GPR , 5-HT Receptor , Melanin-concentrating Hormone Receptor (MCHR) | |
ATC 0175 hydrochloride is an orally active melanocyte concentrating hormone 1 receptor antagonist that is potent and selective. ATC 0175 hydrochloride has affinity for MCH1R, MCH2R, MCH1, 5-HT2B receptors and 5-HT1A rece... | |||
T10173 | MCHR1 antagonist 1 | Others | |
MCHR1 antagonist 1 is a selective antagonist of melanin-concentrating hormone-1 (MCH1) receptor (Kb: 1 nM, Ki: 4 nM at human MCH1). | |||
T26703 | AZ13483342 | AZ-13483342,AZ 13483342 | |
AZ13483342 is an antagonist of the melanin concentrating hormone receptor 1 (MCH1) with a potential diabetes therapeutic activity. | |||
T5406 | SNAP 94847 | SNAP-94847 | GPR , Melanin-concentrating Hormone Receptor (MCHR) |
SNAP 94847 (SNAP-94847) is a selective and competitive MCH1 receptor (MCH1-R) antagonist (Ki: 2.2 nM). It has anxiolytic and antidepressant activity and reduces food intake in mice. | |||
T7749 | ALB-127158 | ||
ALB-127158(a) is a potent and selective melanin concentrating hormone 1 ( MCH 1 ) receptor antagonist which may be a potential treatment for inflammatory bowel disease (IBD). |